Satviki Patidar

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Tissue Based Report Brief summary

Advance Report Result Comment
NGS Pannel DBN1/BRAF (Fussion) Positive Not Detected : ALK,ATRX,EGFR, FGFR1,FGFR2,FGFR3,H3-3A,IDH1, IDH2,MET,MYB,MYBL1, NTRK1,NTRK2,NTRK3, RET,ROS1,TERT,TP53
FISH 1p/19q co-deletion Negative
MGMT Methylation Negative MGMT Promoter methylation
IHC Marker Dr Anita-COP Report Tata Memorial Neuberg Supratech
Tumor Morphology Astrocytic morphology, glial tumor Glial tumor Low-grade glial neoplasm
Cellularity & Pleomorphism Increased cellularity & nuclear pleomorphism Not mentioned Not mentioned
Mitosis Inconspicuous Not mentioned Not seen
Necrosis Not seen Not mentioned Not seen
Microvascular Proliferation Not seen Not mentioned Not seen
Olig2 Positive Positive Negative
IDH1 R132H Negative Negative Negative
ATRX Retained Retained Partially retained nuclear expression
H3K27me3 Retained Underexpressed Not tested
H3K27M Not tested Negative Negative
EZHIP Not tested Negative Not tested
P53 ~15% cells, variable intensity Few cells positive (wild-type pattern) Focal weak (wild-type pattern)
Ki-67 / MIB-1 1–2% 3–5% in highest proliferating areas < 1%
GFAP, S100, Synaptophysin, SOX10 Not tested Not mentioned All positive
Chromogranin, CD34, TTF1 Not tested Not tested All negative
MTAP Not tested Positive Not tested
p16 Not tested Many cells positive Not tested

Google Drive Files

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